Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689487 | 0.81 | RAB9A (0.56) | LMNACYP2C9CYP2D6MEN1GAA | |
| SCHEMBL7668283 | 0.80 | NPSR1 (0.43) | LMNADHODHCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL8686610 | 0.75 | NPSR1 (0.38) | LMNADHODHCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL9393408 | 0.75 | CYP1A2 (0.46) | LMNACYP1A2CYP2C9MEN1GAA | |
| SCHEMBL13228906 | 0.72 | NPSR1 (0.44) | LMNADHODHCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL8185405 | 0.68 | LMNA (0.37) | LMNACYP1A2CYP2C9MEN1GAA | |
| SCHEMBL8684478 | 0.68 | TDP1 (0.67) | LMNACYP1A2CYP2C9CYP2D6MEN1 | |
| SCHEMBL8686614 | 0.68 | KDM4E (0.38) | LMNADHODHCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL5772424 | 0.67 | LMNA (0.49) | LMNACYP1A2CYP2C9CYP2D6MEN1 | |
| SCHEMBL8719716 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756726-A | PHOTOSENSITIZERS | PHARMACYCLICS, INC. (US) | 1998-05-26 | — | — | US | disclosed |