Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223938 | 0.86 | NPC1 (0.39) | P2RX3HDAC1IDO1TGFBR1GSTP1 | |
| SCHEMBL3223927 | 0.86 | NPC1 (0.39) | P2RX3HDAC1IDO1TGFBR1GSTP1 | |
| SCHEMBL8179269 | 0.85 | ALDH1A1 (0.34) | TGFBR1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8173598 | 0.83 | TGFBR1 (0.35) | P2RX3TGFBR1 | |
| SCHEMBL8173594 | 0.82 | TGFBR1 (0.34) | TGFBR1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8189381 | 0.81 | ALDH1A1 (0.35) | HDAC1TGFBR1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8183546 | 0.81 | KMT2A (0.37) | HDAC1TGFBR1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL8185494 | 0.79 | HDAC1 (0.45) | HDAC1IDO1SMN1; SMN2HDAC6KDM4E | |
| SCHEMBL8189383 | 0.78 | TGFBR1 (0.34) | TGFBR1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8182243 | 0.78 | MAPT (0.38) | HDAC1NPC1SMN1; SMN2RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |