Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 6/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 5/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13428522 | 0.90 | CCNA2 (0.36) | ALDH1A1KDM4EHPGDTGFBR1PIM2 | |
| SCHEMBL8173598 | 0.87 | TGFBR1 (0.35) | TGFBR1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL8173594 | 0.86 | TGFBR1 (0.34) | ALDH1A1KDM4EHPGDTGFBR1MEN1 | |
| SCHEMBL13428566 | 0.85 | CCNA2 (0.35) | ALDH1A1KDM4EHPGDTGFBR1FOXO1 | |
| SCHEMBL8179269 | 0.84 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDTGFBR1RAB9A | |
| SCHEMBL8189383 | 0.83 | TGFBR1 (0.34) | ALDH1A1HPGDTGFBR1MEN1KMT2A | |
| SCHEMBL8183546 | 0.81 | KMT2A (0.37) | TGFBR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8185667 | 0.81 | P2RX3 (0.35) | ALDH1A1KDM4EHPGDTGFBR1MEN1 | |
| SCHEMBL13428523 | 0.77 | MCHR1 (0.37) | ALDH1A1KDM4EHPGDTGFBR1MEN1 | |
| SCHEMBL8178636 | 0.77 | TGFBR1 (0.37) | ALDH1A1HPGDTGFBR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |