Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185676 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EPOLBPRSS1 | |
| SCHEMBL8183559 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TP53TSHRLNPEP | |
| SCHEMBL8183563 | 0.86 | ALDH1A1 (0.52) | ALDH1A1TP53TSHRLNPEP | |
| SCHEMBL8185682 | 0.82 | HSD17B10 (0.57) | ALDH1A1HSD17B10KDM4EPOLBNPC1 | |
| SCHEMBL8185554 | 0.81 | MAPT (0.42) | ALDH1A1POLBPRSS1PRSS2PRSS3 | |
| SCHEMBL8185556 | 0.81 | MAPT (0.42) | ALDH1A1POLBPRSS1PRSS2PRSS3 | |
| SCHEMBL7166071 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL7166077 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL8181558 | 0.78 | RARB (0.46) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL8181554 | 0.78 | RARB (0.46) | ALDH1A1NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |