Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.43 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.43 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460000 | 0.84 | SMYD3 (0.55) | SMYD3GAAALDH1A1SMN1; SMN2PRKCI | |
| SCHEMBL3462385 | 0.84 | SMYD3 (0.55) | SMYD3GAAALDH1A1SMN1; SMN2PRKCI | |
| SCHEMBL3460185 | 0.77 | SMYD3 (0.53) | SMYD3GAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3460359 | 0.77 | SMYD3 (0.53) | SMYD3GAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3462774 | 0.77 | SMYD3 (0.53) | SMYD3GAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3463033 | 0.76 | NAMPT (0.49) | SMYD3ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL3461687 | 0.76 | NAMPT (0.49) | SMYD3ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL22757714 | 0.75 | ALDH1A1 (0.55) | ALDH1A1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL8181659 | 0.73 | ALDH1A1 (0.54) | SMYD3ALDH1A1PSMB11PSMA7PSMB1 | |
| SCHEMBL34468382 | 0.69 | SIGMAR1 (0.58) | GAAALDH1A1KDM1ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074035-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2008-06-19 | — | — | WO | disclosed |