Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186684 | 0.88 | ACACB (0.38) | SMN1; SMN2SCDACACB | |
| SCHEMBL8175327 | 0.85 | GRM4 (0.34) | SCD | |
| SCHEMBL8186674 | 0.82 | PYGL (0.38) | — | |
| SCHEMBL8186495 | 0.81 | MAOB (0.36) | SMN1; SMN2MAPK1 | |
| SCHEMBL8185025 | 0.80 | EGLN1 (0.40) | — | |
| SCHEMBL8184417 | 0.75 | EGLN1 (0.41) | SCD | |
| SCHEMBL8184265 | 0.75 | EGLN1 (0.41) | SCD | |
| SCHEMBL8179729 | 0.74 | ACACB (0.35) | SMN1; SMN2SCDAPPACACB | |
| SCHEMBL8189038 | 0.73 | PGK1 (0.38) | SMN1; SMN2ACACB | |
| SCHEMBL8188941 | 0.72 | ACACB (0.39) | SMN1; SMN2MAPK1SCDACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077557-A1 | 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2008-07-03 | — | — | WO | disclosed |