Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153413 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL8200273 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL11125930 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL8352923 | 0.94 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| Iodide SCHEMBL10378669 | 0.85 | USP2 (0.49) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL11154511 | 0.84 | KDM4E (0.58) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL9751080 | 0.83 | ALDH1A1 (0.57) | ALDH1A1USP2KDM4EALOX15HTT | |
| SCHEMBL23673724 | 0.82 | USP2 (0.71) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL8394063 | 0.82 | USP2 (0.71) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 | |
| SCHEMBL11151192 | 0.82 | LMNA (0.57) | SMN1; SMN2ALDH1A1USP2KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059906-A1 | AMINOHETEROCYCLE-SUBSTITUTED GLYCEROLS | CLARION PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |