Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190284 | 0.88 | ATM (0.44) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8200553 | 0.88 | NISCH (0.60) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8219724 | 0.88 | TOP2A (0.43) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8197166 | 0.88 | NISCH (0.60) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8195231 | 0.87 | NISCH (0.55) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8197475 | 0.86 | MAOB (0.49) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8196690 | 0.83 | RARA (0.45) | TOP2ATOP2BNISCHS1PR1ALDH1A1 | |
| SCHEMBL8196239 | 0.81 | LMNA (0.47) | LMNARECQLMAOBTOP2ATOP2B | |
| SCHEMBL8187862 | 0.81 | NISCH (0.56) | MAOBTOP2ATOP2BNISCHALDH1A1 | |
| SCHEMBL8187056 | 0.79 | NISCH (0.53) | LMNARECQLMAOBTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |