Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.66 |
| ▸ | PARP1 | P09874 | 4/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894080 | 0.91 | PARP10 (0.78) | PARP11PARP10PARP1PDPK1CA12 | |
| SCHEMBL20076060 | 0.86 | PARP10 (0.75) | PARP11PARP10PARP1PDPK1CA12 | |
| SCHEMBL29752161 | 0.86 | PARP10 (0.75) | PARP11PARP10PARP1PDPK1CA12 | |
| SCHEMBL29369705 | 0.80 | PARP10 (1.00) | PARP11PARP10PARP1PDPK1CA12 | |
| SCHEMBL67710 | 0.80 | PARP10 (1.00) | PARP11PARP10PARP1PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL29896921 | 0.78 | PARP10 (0.96) | PARP11PARP10PARP1PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL10647408 | 0.78 | PARP10 (0.96) | PARP11PARP10PARP1PDPK1CA12 | |
| Trifluoroacetic Acid SCHEMBL28415123 | 0.78 | PARP10 (0.72) | PARP11PARP10PARP1PDPK1CA12 | |
| Oxalic Acid SCHEMBL7825836 | 0.77 | MAPT (0.56) | CA12CA9MAPTKDM4ECASP7 | |
| Piperazine SCHEMBL28321362 | 0.75 | PARP10 (0.89) | PARP11PARP10PARP1PDPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107308-A | ANTIHISTAMINE; LEUTRIENE ANTAGONIST | KOWA CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |