SCHEMBL8188034

SCHEMBL8188034

CCCC(N)N(C(N)CC)C1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 3/20 0.33
ADH1C P00326 2/20 0.33
SHBG P04278 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11771019 0.87 SHBG (0.41) ADH1AADH1CSHBG
SCHEMBL15303113 0.72 SHBG (0.39) ADH1AADH1CSHBG
SCHEMBL28990600 0.72 DPP4 (0.33) ADH1AADH1CSHBG
SCHEMBL15303050 0.71 SHBG (0.38) ADH1AADH1CSHBG
SCHEMBL4791863 0.69 SMN1; SMN2 (0.37) ADH1AADH1C
SCHEMBL28984361 0.68 ADH1A (0.36) ADH1AADH1C
SCHEMBL10772891 0.64 ADH1A (0.33) ADH1AADH1CSHBG
SCHEMBL10584964 0.64 SHBG (0.39) ADH1AADH1CSHBG
SCHEMBL19333316 0.63 ADH1A (0.40) ADH1AADH1CSHBG
SCHEMBL23736378 0.63 ADH1A (0.39) ADH1AADH1CSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed