Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20321837 | 0.80 | SHBG (0.35) | ADH1AADH1CSLC2A1SHBG | |
| SCHEMBL10710852 | 0.77 | ADH1A (0.39) | ADH1AADH1C | |
| SCHEMBL17914491 | 0.75 | ADH1A (0.45) | ADH1AADH1C | |
| SCHEMBL19333315 | 0.74 | ADH1A (0.44) | ADH1AADH1CSLC2A1SHBG | |
| SCHEMBL17914487 | 0.74 | ADH1A (0.47) | ADH1AADH1CSHBG | |
| SCHEMBL22201718 | 0.73 | SLC2A1 (0.38) | ADH1AADH1CSLC2A1SHBG | |
| SCHEMBL13463996 | 0.73 | THRA (0.35) | ADH1AADH1C | |
| SCHEMBL14219530 | 0.71 | THRA (0.34) | ADH1AADH1C | |
| SCHEMBL20321625 | 0.67 | PIK3CD (0.50) | — | |
| SCHEMBL24693895 | 0.67 | DRD2 (0.33) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |