Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7111495 | 0.82 | PNMT (0.37) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL820366 | 0.81 | PNMT (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL719838 | 0.80 | NPC1 (0.40) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL715374 | 0.80 | PNMT (0.35) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL216029 | 0.80 | PNMT (0.35) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL4867504 | 0.79 | PNMT (0.37) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL818806 | 0.79 | PNMT (0.34) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7032668 | 0.78 | PNMT (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL818262 | 0.78 | NPC1 (0.36) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL819906 | 0.78 | PNMT (0.34) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982236-B2 | Process to polymerize olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-03 | — | — | US | claimed |
| US-6897273-B2 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2005-05-24 | — | — | US | claimed |
| EP-1392743-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | Univation Technologies LLC (US) | 2004-03-03 | — | — | EP | claimed |
| US-20040039138-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2004-02-26 | — | — | US | claimed |
| US-6656866-B2 | Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2003-12-02 | — | — | US | claimed |
| US-20030207762-A9 | CATALYST PREPARATION METHOD | UNIVATION TECHNOLOGIES, LLC | 2003-11-06 | — | — | US | claimed |
| EP-1358216-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | Univation Technologies LLC (US) | 2003-11-05 | — | — | EP | claimed |
| US-6620894-B2 | Calibration; using coordination catalyst | UNIVATION TECHNOLOGIES, LLC | 2003-09-16 | — | — | US | claimed |
| US-20020132937-A1 | Start-up procedure for multiple catalyst polymerization systems | UNIVATION TECHNOLOGIES, LLC | 2002-09-19 | — | — | US | claimed |
| US-20020119890-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2002-08-29 | — | — | US | claimed |
| US-20020103310-A1 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC | 2002-08-01 | — | — | US | claimed |
| WO-2002050127-A2 | START-UP PROCEDURE FOR MULTIPLE CATALYST POLYMERIZATION SYSTEMS | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-27 | — | — | WO | claimed |
| WO-2002046250-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-13 | — | — | WO | claimed |
| US-20260103548-A1 | PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY | W. R. GRACE & CO.-CONN. | 2026-04-16 | — | — | US | disclosed |
| US-20250235859-A1 | PROCESS FOR PRODUCING A SINGLE SITE CATALYST | W.R. GRACE & CO.-CONN. (US) | 2025-07-24 | — | — | US | disclosed |
| US-20250205686-A1 | SILICA-SUPPORTED POLYOLEFIN CATALYST SYSTEM | W. R. GRACE & CO.-CONN. | 2025-06-26 | — | — | US | disclosed |
| EP-0593083-B1 | Gas phase polymerization reaction utilizing soluble unsupported catalysts | UNION CARBIDE CHEM PLASTIC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0668295-A1 | Spray dried, filled metallocene catalyst composition for use in polyolefin manufacture | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5317036-A | Continuous catalytic vapor phase polymerization of olefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-05-31 | — | — | US | disclosed |
| EP-0593083-A1 | Gas phase polymerization reaction utilizing soluble unsupported catalysts | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103548-A1 | PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY | CCT4, PTGER1, TCP1 | PNMT 1317/4885NPC1 4558/4885RAB9A 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.