Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390466 | 0.96 | NPC1 (0.39) | NPC1RAB9AALDH1A1PNMTHTR7 | |
| Hydrochloric Acid SCHEMBL7918192 | 0.88 | NPC1 (0.37) | NPC1RAB9AALDH1A1PNMTHTR7 | |
| Hydrochloric Acid SCHEMBL818262 | 0.88 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL820366 | 0.86 | PNMT (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL820387 | 0.86 | NPC1 (0.35) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL714922 | 0.85 | NPC1 (0.49) | NPC1RAB9AALDH1A1PNMTHTR7 | |
| Hydrochloric Acid SCHEMBL818806 | 0.83 | PNMT (0.34) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7913315 | 0.83 | NPC1 (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL5081113 | 0.83 | PNMT (0.34) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7913311 | 0.83 | NPC1 (0.33) | NPC1RAB9APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469701-B2 | Polyethylene powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20160137760-A1 | Polyethylene Powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053311-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20110288250-A1 | Copolymer and Production Process Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |
| US-8044159-B2 | Homopolymer and copolymer, and production process thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-25 | — | — | US | disclosed |
| WO-2011074688-A1 | PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | WO | disclosed |
| US-7964691-B2 | 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-21 | — | — | US | disclosed |
| US-7956145-B2 | Polymerization of 1,6-heptadiene in the presence of a catalyst formed by contacting a transition metal with a diimino aluminum or boron compound, giving a polymer structure of alternating ethylene and cyclopentene; superior balance between a heat resistance and workability | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-07 | — | — | US | disclosed |
| US-7943715-B2 | Polymerization of 1,6-heptadiene in the presence of a catalyst formed by contacting a transition metal with a diimino aluminum or boron compound, giving a polymer structure of alternating ethylene and cyclopentene; superior balance between a heat resistance and workability | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-0591841-B1 | Process for producing styrenic polymer | IDEMITSU KOSAN CO (JP) | 1997-04-09 | — | — | EP | disclosed |
| EP-0570982-B1 | Catalysts and process for producing olefin polymers | TOSOH CORP (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5576259-A | POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE | TOSOH CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0653445-A1 | Ethylene/alpha-olefin copolymer | Tosoh Corporation (JP) | 1995-05-17 | — | — | EP | disclosed |
| EP-0648786-A1 | Process for producing alpha-olefin polymer | Tosoh Corporation (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0612769-A1 | Process for producing ethylene alpha-olefin copolymer | TOSOH CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0591841-A1 | Process for producing styrenic polymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0570982-A1 | Catalysts and process for producing olefin polymers | TOSOH CORPORATION (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0505973-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |
| EP-0505972-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | PPOX, SOD1, AP1M1 | NPC1 4275/4885RAB9A 3823/4885ALDH1A1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.