Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177983 | 0.89 | TSHR (0.47) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL24137712 | 0.85 | POLB (0.60) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL138832 | 0.79 | KMT2A (0.50) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL8866414 | 0.79 | TSHR (0.45) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL21138360 | 0.79 | TSHR (0.55) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL7601879 | 0.79 | TSHR (0.55) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL9809369 | 0.78 | KMT2A (0.46) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL18463247 | 0.78 | TSHR (0.47) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL9373811 | 0.78 | L3MBTL1 (0.53) | TSHRRECQLL3MBTL1ALDH1A1POLB | |
| SCHEMBL10985089 | 0.77 | ALDH1A1 (0.72) | TSHRRECQLL3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100246-A | Spiro-piperidine derivatives as inhibitors of nitric oxide synthase | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| US-5453422-A | Animal growth promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5284842-A | Active against gramnegative bacteria | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5173484-A | Animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |