Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138832 | 0.87 | KMT2A (0.50) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14239663 | 0.82 | USP2 (0.45) | TSHRSMN1; SMN2HPGDRECQL | |
| SCHEMBL8866815 | 0.81 | KMT2A (0.45) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8866810 | 0.81 | KMT2A (0.45) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8188669 | 0.78 | TSHR (0.55) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL31722398 | 0.76 | LMNA (0.51) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9177983 | 0.72 | TSHR (0.47) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10339106 | 0.71 | KMT2A (0.49) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| Ethylene SCHEMBL8866321 | 0.71 | KMT2A (0.46) | KMT2ATSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12994041 | 0.71 | TSHR (0.53) | KMT2ATSHRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075317-A | 2,8-dimethyl-1-oxa-8-azospiro(4.5) decan-3-one; alzheimer*s di sease | FISONS CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |