Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817755 | 0.92 | TSHR (0.42) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL818110 | 0.92 | L3MBTL1 (0.41) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL817763 | 0.91 | ALDH1A1 (0.43) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL819433 | 0.87 | GAA (0.40) | ALDH1A1LMNATSHRHPGDRAB9A | |
| SCHEMBL817269 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CHRM1TSHRNPC1RAB9A | |
| SCHEMBL819727 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRTDP1HSD17B10 | |
| SCHEMBL818058 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL818207 | 0.75 | KCNH2 (0.38) | ALDH1A1LMNATSHRTDP1PTPN1 | |
| SCHEMBL30483874 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNACHRM1ESR1TSHR | |
| SCHEMBL818061 | 0.74 | ALDH1A1 (0.36) | ALDH1A1LMNACHRM1ESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |