Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.55 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199557 | 0.86 | MCL1 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6940805 | 0.84 | MCL1 (0.62) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8398928 | 0.84 | MCL1 (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9306580 | 0.84 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8401426 | 0.82 | MCL1 (0.61) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8196770 | 0.81 | MCL1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8200379 | 0.79 | MAPT (0.42) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL9219841 | 0.77 | MCL1 (0.63) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8196778 | 0.74 | MCL1 (0.59) | MCL1KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8200416 | 0.74 | PIM1 (0.49) | MCL1KDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36832-E | AN ANTICHOLESTEROL AGENT TREATING HYPERCHOLESTEROLEMIA | NIHON NOHYAKU CO., LTD (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0613894-B1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5464863-A | Anticholesterol agents | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0613894-A1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |