Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | DRD3 | P35462 | 4/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556792 | 0.85 | DRD2 (0.68) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| SCHEMBL21204694 | 0.82 | ALDH1A1 (0.63) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| SCHEMBL8764445 | 0.78 | DRD2 (0.68) | ALDH1A1DRD2DRD3KDM4EHTR1A | |
| SCHEMBL3704117 | 0.78 | KDM4E (0.63) | ALDH1A1DRD2DRD3KDM4EHTR1A | |
| SCHEMBL6635193 | 0.78 | KDM4E (0.62) | ALDH1A1DRD2DRD3MAPTKDM4E | |
| SCHEMBL8764218 | 0.78 | DRD2 (0.68) | ALDH1A1DRD2DRD3KDM4EHTR1A | |
| SCHEMBL8764223 | 0.78 | DRD2 (0.68) | ALDH1A1DRD2DRD3KDM4EHTR1A | |
| SCHEMBL26418370 | 0.78 | DRD2 (0.71) | ALDH1A1DRD2DRD3HTR3EHTR3B | |
| SCHEMBL8764013 | 0.77 | KDM4E (0.84) | ALDH1A1DRD2DRD3KDM4EHTR1A | |
| SCHEMBL8764010 | 0.77 | KDM4E (0.84) | ALDH1A1DRD2DRD3KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063168-A1 | SYNTHESIS OF AZETIDINE DERIVATIVES | COELACANTH CHEMICAL CORPORATION (US) | 2000-10-26 | — | — | WO | disclosed |