Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8176086 | 0.85 | MAPT (0.45) | MEN1KMT2AMAPK1SMN1; SMN2USP2 | |
| SCHEMBL8176766 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2GPX4MAPT | |
| SCHEMBL8184192 | 0.81 | NR1H4 (0.45) | MEN1KMT2AKDRMAPK1SMN1; SMN2 | |
| SCHEMBL8184224 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAP3K5KLKB1KDR | |
| SCHEMBL8189042 | 0.81 | MEN1 (0.53) | MEN1KMT2AKDRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8184284 | 0.81 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2GPX4MAPT | |
| SCHEMBL7109075 | 0.80 | MAPT (0.50) | MEN1KMT2AMAP3K5MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8187880 | 0.80 | NR1H4 (0.45) | MEN1KMT2AKDRMAPK1SMN1; SMN2 | |
| SCHEMBL8175630 | 0.79 | RAB9A (0.56) | MEN1KMT2AMAPK1SMN1; SMN2RXFP1 | |
| SCHEMBL8185113 | 0.79 | MAPK1 (0.47) | MEN1KMT2AMAPK1SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |