Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8182718 | 0.99 | KDR (0.45) | KDRKMT2AALDH1A1KDM4EABCB1 | |
| SCHEMBL8187672 | 0.93 | ALDH1A1 (0.50) | KDRKMT2AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8185493 | 0.92 | ALDH1A1 (0.49) | KDRKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8175290 | 0.88 | KMT2A (0.48) | KMT2AALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL8440274 | 0.85 | ALDH1A1 (0.38) | KDRKMT2AALDH1A1KDM4EABCB1 | |
| SCHEMBL8183726 | 0.84 | KMT2A (0.44) | KDRKMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8174378 | 0.84 | KMT2A (0.42) | KDRKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8184601 | 0.82 | KMT2A (0.49) | KMT2AALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL8176080 | 0.82 | KMT2A (0.51) | KMT2AALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL8184226 | 0.82 | KMT2A (0.46) | KDRKMT2AMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110934-A | Substituted benzamide derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-08-29 | — | — | US | disclosed |