Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189705 | 0.85 | KDR (0.46) | ALDH1A1POLBKDRABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL8182718 | 0.84 | KDR (0.45) | ALDH1A1POLBKDRABCB1ABCG2 | |
| SCHEMBL8187672 | 0.83 | ALDH1A1 (0.50) | ALDH1A1POLBKDRKMT2APSMD14 | |
| Hydrochloric Acid SCHEMBL8185493 | 0.82 | ALDH1A1 (0.49) | ALDH1A1POLBKDRKMT2APSMD14 | |
| SCHEMBL8174345 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1POLBKMT2AMAPTLMNA | |
| SCHEMBL8175290 | 0.81 | KMT2A (0.48) | ALDH1A1POLBKMT2AMAPTLMNA | |
| SCHEMBL8185203 | 0.80 | KMT2A (0.48) | ALDH1A1POLBKMT2AMAPTLMNA | |
| SCHEMBL8183726 | 0.78 | KMT2A (0.44) | ALDH1A1POLBKDRKMT2ASMN1; SMN2 | |
| SCHEMBL8174378 | 0.77 | KMT2A (0.42) | ALDH1A1POLBKDRKMT2AMAPT | |
| SCHEMBL7799966 | 0.77 | KMT2A (0.45) | POLBKMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906283-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997048683-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1997-12-24 | — | — | WO | disclosed |