SCHEMBL8189804

SCHEMBL8189804

CNC(=O)C[C@@H](CO)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.69
SLC6A3 Q01959 1/20 0.51
MAPT P10636 1/20 0.51
GABBR2 O75899 1/20 0.44
GABBR1 Q9UBS5 1/20 0.44
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
FNTA P49354 3/20 0.42
FNTB P49356 3/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8178115 1.00 ATM (0.69) ATMSLC6A3MAPTGABBR2GABBR1
SCHEMBL8194695 1.00 ATM (0.69) ATMSLC6A3MAPTGABBR2GABBR1
SCHEMBL9538880 0.91 ATM (0.81) ATMSLC6A3MAPTGABBR2GABBR1
SCHEMBL8333167 0.86 ATM (0.73) ATMSLC6A3MAPTGABBR2GABBR1
SCHEMBL8188576 0.83 HPGD (0.50) ATMMAPTGABBR2GABBR1KDM4E
SCHEMBL8188743 0.83 HPGD (0.50) ATMMAPTGABBR2GABBR1KDM4E
SCHEMBL8179050 0.83 HPGD (0.50) ATMMAPTGABBR2GABBR1KDM4E
SCHEMBL8186893 0.82 ALDH1A1 (0.50) ATMSLC6A3MAPTLMNAFNTA
SCHEMBL362441 0.81 LMNA (0.62) ATMSLC6A3POLBLMNA
SCHEMBL8178529 0.80 L3MBTL1 (0.50) ATMMAPTPOLBLMNAFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801642-B1 NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME YUKONG LTD (KR) 2000-12-20 EP disclosed
US-5892088-A Sulfamate compound containing N-substituted carbamoyl group and method for preparing the same YUKONG LIMITED (KR) 1999-04-06 US disclosed
EP-0801642-A1 NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME YUKONG LIMITED (KR) 1997-10-22 EP disclosed
WO-1997016418-A1 NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME YUKONG LIMITED (KR) 1997-05-09 WO disclosed