Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.34 |
| ▸ | ADH1A | P07327 | 2/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183845 | 0.81 | ADH1B (0.50) | LOXL2HSD17B10KCNQ2ADH1BADH1A | |
| SCHEMBL1302123 | 0.79 | TDP1 (0.46) | LOXL2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1661204 | 0.79 | LOXL2 (0.48) | LOXL2HSD17B10KCNQ2HCAR2 | |
| SCHEMBL1303904 | 0.76 | CYP1A2 (0.53) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8763412 | 0.75 | LMNA (0.50) | ADH1BADH1AADH7ADH1CLMNA | |
| SCHEMBL18162782 | 0.75 | TAAR1 (0.48) | LOXL2HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL20037805 | 0.71 | GAA (0.53) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5361823 | 0.71 | LMNA (0.36) | HSD17B10ADH1BADH1AADH7ADH1C | |
| SCHEMBL8691993 | 0.71 | — | — | |
| SCHEMBL8191341 | 0.71 | ADH1B (0.34) | ADH1BADH1AADH7ADH1CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |