Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36714 | 0.86 | TSHR (0.45) | TSHRTP53LMNANPC1SMN1; SMN2 | |
| SCHEMBL8756311 | 0.82 | RAB9A (0.45) | TSHRTP53LMNANPC1SMN1; SMN2 | |
| SCHEMBL9166635 | 0.80 | TSHR (0.52) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5189160 | 0.80 | CA12 (0.41) | TSHRPDCD1CD274LMNANPC1 | |
| SCHEMBL10731368 | 0.80 | PTPN2 (0.38) | TSHRNPC1SMN1; SMN2ALDH1A1SCN1A | |
| Acetic Acid SCHEMBL1273751 | 0.79 | TSHR (0.59) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL6660758 | 0.79 | TSHR (0.63) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL6015660 | 0.79 | TSHR (0.50) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL8190350 | 0.78 | TSHR (0.49) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL11144462 | 0.78 | LMNA (0.50) | TSHRTP53PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022664-A | MIXTURE OF A POLYMERIZABLE VINYL MONOMER AND ORGANIC BORATE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 2000-02-08 | — | — | US | disclosed |