Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190492 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTMAOBESR1CYP1A2 | |
| SCHEMBL8182494 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1RAB9AHPGD | |
| SCHEMBL8182492 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1RAB9AHPGD | |
| SCHEMBL17615977 | 0.76 | MMP2 (0.51) | ALDH1A1MAPTMMP2HPGDPOLB | |
| SCHEMBL14548246 | 0.76 | MMP2 (0.51) | ALDH1A1MAPTMMP2HPGDPOLB | |
| SCHEMBL20053879 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTMAOBESR1CYP1A2 | |
| SCHEMBL3372818 | 0.72 | MAPT (0.62) | ALDH1A1MAPTESR1CYP1A2CYP3A4 | |
| SCHEMBL4770909 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTMAOBESR1CYP1A2 | |
| SCHEMBL20053889 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTMAOBESR1CYP1A2 | |
| SCHEMBL2163526 | 0.69 | L3MBTL1 (0.57) | ALDH1A1MAPTESR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032586-A1 | METHOD FOR PREPARING 3-CHROMENE DERIVATIVES, USE OF SAID DERIVATIVES FOR PREPARING THIAZOLIDINONES | RHODIA CHIMIE (FR) | 2000-06-08 | — | — | WO | disclosed |