Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TFEB | P19484 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819054 | 0.84 | CA1 (0.56) | LMNAMAPTNFKB1KDM4ECA1 | |
| SCHEMBL28414685 | 0.84 | CA1 (0.56) | LMNAMAPTNFKB1KDM4ECA1 | |
| SCHEMBL2328371 | 0.80 | NFKB1 (0.50) | PTPN1LMNAMAPTCCNCCDK8 | |
| SCHEMBL13299432 | 0.79 | KDM4E (0.47) | LMNAMAPTCCNCCDK8NFE2L2 | |
| SCHEMBL28319094 | 0.78 | TYR (0.44) | PTPN1LMNAMAPTCCNCCDK8 | |
| SCHEMBL20030395 | 0.77 | HDAC8 (0.41) | LMNAMAPTKDM4EKMT2AHPGD | |
| SCHEMBL2010382 | 0.77 | NOS3 (0.40) | PTPN1LMNAMAPTCCNCCDK8 | |
| SCHEMBL9194659 | 0.76 | GABRA1 (0.46) | LMNAMAPTGABRA1GABRB2NFE2L2 | |
| SCHEMBL28909604 | 0.76 | CA12 (0.49) | LMNAMAPTCCNCCDK8KDM4E | |
| SCHEMBL21716655 | 0.76 | CA12 (0.49) | LMNAMAPTCCNCCDK8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274546-A1 | New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds | AMERICAN CYANAMID COMPANY (US) | 1988-07-20 | — | — | EP | claimed |