Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.47 |
| ▸ | MMP12 | P39900 | 18/20 | 0.47 |
| ▸ | MMP9 | P14780 | 16/20 | 0.47 |
| ▸ | MMP2 | P08253 | 13/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416800 | 0.79 | MMP1 (0.53) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL17261572 | 0.74 | MMP1 (0.53) | MMP1MMP12MMP9MMP2NOTUM | |
| SCHEMBL20206904 | 0.73 | MMP1 (0.56) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL13571768 | 0.73 | MMP1 (0.52) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL21322002 | 0.73 | MMP1 (0.52) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL24112333 | 0.68 | MMP1 (0.51) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1161224 | 0.68 | MMP1 (0.66) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL2897889 | 0.68 | MMP1 (0.47) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL3724190 | 0.68 | MMP1 (0.51) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL31453250 | 0.66 | POLB (0.46) | MMP1MMP12MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109180-A2 | METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-09-12 | — | — | WO | disclosed |