Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 19/20 | 0.56 |
| ▸ | MMP12 | P39900 | 18/20 | 0.56 |
| ▸ | MMP9 | P14780 | 17/20 | 0.56 |
| ▸ | MMP2 | P08253 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416800 | 0.79 | MMP1 (0.53) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL13571768 | 0.77 | MMP1 (0.52) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL24112333 | 0.77 | MMP1 (0.51) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL3724190 | 0.77 | MMP1 (0.51) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1161224 | 0.77 | MMP1 (0.66) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL16012524 | 0.76 | THRB (0.37) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL18744693 | 0.75 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL17261572 | 0.74 | MMP1 (0.53) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL8190893 | 0.73 | MMP1 (0.47) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL9354140 | 0.72 | MMP1 (0.60) | MMP1MMP12MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |