SCHEMBL819176

SCHEMBL819176

Cl[Ru](Cl)(=Cc1ccccc1)(=C1N(C2CCCCC2)CCN1C1CCCCC1)=C1N(C2CCCCC2)CCN1C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.38
SLC18A3 Q16572 1/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 3/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 2/20 0.36
CHRM3 P20309 2/20 0.32
CHRM2 P08172 1/20 0.32
POLB P06746 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819175 0.76 IL4I1 (0.34) SLC18A3ALDH1A1KDM4EGAAPOLB
SCHEMBL30785383 0.76 SLC18A3 (0.34) SLC18A3ALDH1A1KDM4EGAAHPGD
SCHEMBL4607065 0.69 HSD11B1 (0.39) HSD11B1SLC18A3ALDH1A1KDM4EGAA
Hydrochloric Acid SCHEMBL1006742 0.69 HSD11B1 (0.39) HSD11B1SLC18A3ALDH1A1KDM4EGAA
Hydrochloric Acid SCHEMBL852064 0.68 HSD11B1 (0.38) HSD11B1SLC18A3ALDH1A1KDM4EGAA
SCHEMBL818809 0.67 CYP2D6 (0.34) HPGD
SCHEMBL29355518 0.66 GAA (0.36) KDM4EGAAHPGDPOLBSMN1; SMN2
SCHEMBL4523228 0.65 HPGD (0.32) KDM4EHPGDLMNASMN1; SMN2
SCHEMBL28898023 0.65 HSD11B1 (0.34) HSD11B1SLC18A3ALDH1A1KDM4EGAA
SCHEMBL1172657 0.65 SLC18A3 (0.33) HSD11B1SLC18A3ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4640736-A1 RING-OPENED COPOLYMER, RUBBER COMPOSITION, RUBBER CROSS-LINKED PRODUCT, AND TIRE Zeon Corporation (JP) 2025-10-29 EP disclosed
US-20250263511-A1 COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOOLEFIN, PRODUCTION METHOD THEREFOR, RUBBER COMPOSITION, AND CROSSLINKED RUBBER OBJECT ZEON CORPORATION (JP) 2025-08-21 US disclosed
US-20250215136-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT ZEON CORPORATION (JP) 2025-07-03 US disclosed
US-20250215137-A1 COPOLYMER, RUBBER COMPOSITION AND CROSSLINKED RUBBER ZEON CORPORATION (JP) 2025-07-03 US disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025070000-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER, AND TIRE 日本ゼオン株式会社 2025-04-03 WO disclosed
US-20040095792-A1 Alkylidene complexes of ruthenium containing N-heterocyclic carbene ligands; use as highly active, selective catalysts for olefin metathesis HERRMANN WOLFGANG ANTON (DE) 2004-05-20 US disclosed
EP-1408064-A1 OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS Zeon Corporation (JP) 2004-04-14 EP disclosed
US-6635768-B1 Inexpensive, highly active catalysts; high tolerance toward a variety of functional groups but also a wide range of possible variations in the ligand sphere DEGUSSA AG (DE) 2003-10-21 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed
EP-1087838-A1 ALKYLIDENE COMPLEXES OF RUTHENIUM WITH N-HETEROCYCLIC CARBENE LIGANDS AND THEIR USE AS HIGHLY ACTIVE, SELECTIVE CATALYSTS FOR OLEFIN METATHESIS Aventis Research & Technologies GmbH & Co. KG (DE) 2001-04-04 EP disclosed
WO-1999051344-A1 ALKYLIDENE COMPLEXES OF RUTHENIUM WITH N-HETEROCYCLIC CARBENE LIGANDS AND THEIR USE AS HIGHLY ACTIVE, SELECTIVE CATALYSTS FOR OLEFIN METATHESIS AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-10-14 WO disclosed