Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1006782 | 0.76 | SLC18A3 (0.35) | SLC18A3NPSR1GAAALDH1A1KDM4E | |
| SCHEMBL4607065 | 0.71 | HSD11B1 (0.39) | HSD11B1SLC18A3HPGDGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL852064 | 0.70 | HSD11B1 (0.38) | HSD11B1SLC18A3HPGDGAAALDH1A1 | |
| SCHEMBL819176 | 0.69 | HSD11B1 (0.38) | HSD11B1SLC18A3HPGDGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1007232 | 0.68 | HSD11B1 (0.35) | HSD11B1SLC18A3HPGDGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6100085 | 0.66 | HSD11B1 (0.33) | HSD11B1SLC18A3HPGDNPSR1GAA | |
| SCHEMBL28898023 | 0.64 | HSD11B1 (0.34) | HSD11B1SLC18A3HPGDGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL1172655 | 0.64 | KDM4E (0.34) | SLC18A3NPSR1GAAALDH1A1KDM4E | |
| SCHEMBL12230209 | 0.61 | SLC18A3 (0.50) | SLC18A3ALDH1A1KDM4ELMNAHRH3 | |
| SCHEMBL1043568 | 0.61 | OPRM1 (0.43) | HSD11B1SLC18A3GAAOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215136-A1 | RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT | ZEON CORPORATION (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250215137-A1 | COPOLYMER, RUBBER COMPOSITION AND CROSSLINKED RUBBER | ZEON CORPORATION (JP) | 2025-07-03 | — | — | US | disclosed |
| US-20250091969-A1 | CYCLOPENTENE RECOVERY METHOD | ZEON CORPORATION (JP) | 2025-03-20 | — | — | US | disclosed |
| EP-4502014-A1 | COPOLYMER, RUBBER COMPOSITION AND CROSSLINKED RUBBER | Zeon Corporation (JP) | 2025-02-05 | — | — | EP | disclosed |
| EP-4502059-A1 | RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT | Zeon Corporation (JP) | 2025-02-05 | — | — | EP | disclosed |
| WO-2025013873-A1 | CYCLOPENTENE RECOVERY METHOD | 日本ゼオン株式会社 | 2025-01-16 | — | — | WO | disclosed |
| EP-4461720-A1 | CYCLOPENTENE RECOVERY METHOD | Zeon Corporation (JP) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023132366-A1 | CYCLOPENTENE RECOVERY METHOD | 日本ゼオン株式会社 | 2023-07-13 | — | — | WO | disclosed |
| US-9570641-B2 | Polymer and solar cell encapsulant using the polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |
| EP-2270063-B1 | PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION | ZEON CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-1589055-A1 | PROCESS FOR PRODUCING CYCLOOLEFIN RESIN FILM AND PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER SHEET OR FILM | Zeon Corporation (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-20050148746-A1 | Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these | ZEON CORPORATION (JP) | 2005-07-07 | — | — | US | disclosed |
| US-6908970-B2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION (JP) | 2005-06-21 | — | — | US | disclosed |
| EP-1535941-A1 | PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS | ZEON CORPORATION (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6815516-B2 | HEAT RESISTANCE, SOLVENT SOLUBILITY | ZEON CORPORATION (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20030050406-A1 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION | 2003-03-13 | — | — | US | disclosed |
| US-20030018138-A1 | Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these | ZEON CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1275675-A1 | COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE | Zeon Corporation (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6486264-B1 | Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin | ZEON CORPORATION (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1197509-A1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | Nippon Zeon Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091969-A1 | CYCLOPENTENE RECOVERY METHOD | CYC1, CYCS, DHPS | HSD11B1 310/4885SLC18A3 3263/4885HPGD 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.