Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991584 | 0.83 | ALOX5 (0.54) | ALOX5MAOBHTR1ADRD2LMNA | |
| SCHEMBL28330023 | 0.83 | ALOX5 (0.54) | ALOX5MAOBHTR1ADRD2LMNA | |
| SCHEMBL3022918 | 0.80 | HTR1A (0.67) | HTR1ADRD2LMNAGAAMAPT | |
| SCHEMBL13412635 | 0.80 | ALOX5 (0.63) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL6203294 | 0.80 | MAOB (0.51) | ALOX5MAOBHTR1ADRD2LMNA | |
| SCHEMBL7823412 | 0.80 | PTGER1 (0.54) | ALOX5MAOB | |
| SCHEMBL27742512 | 0.79 | S1PR1 (0.54) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27515475 | 0.79 | MAOB (0.54) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL2090973 | 0.78 | ALOX5 (0.56) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL4951735 | 0.78 | ALOX5 (0.51) | ALOX5MAOBHTR1ADRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043227-A | C11 carbamates of macrolide antibacterials | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |