Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774223 | 0.87 | ALOX5 (0.54) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL1587667 | 0.85 | MRGPRX4 (0.46) | ALOX5HTR1ADRD2MTNR1AMTNR1B | |
| SCHEMBL8192001 | 0.83 | ALOX5 (0.54) | ALOX5MAOBHTR1ADRD2LMNA | |
| SCHEMBL28330023 | 0.83 | ALOX5 (0.54) | ALOX5MAOBHTR1ADRD2LMNA | |
| SCHEMBL4720836 | 0.83 | PTGER1 (0.56) | — | |
| SCHEMBL2868493 | 0.83 | LTA4H (0.51) | HTR1ADRD2LMNASLC6A2SLC6A3 | |
| SCHEMBL7446429 | 0.82 | ALOX5 (0.53) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL7450663 | 0.82 | HTR1A (0.51) | HTR1ADRD2LMNAGAAMAPT | |
| SCHEMBL27134824 | 0.82 | CCR5 (0.62) | MAOBLMNARAB9ASMN1; SMN2 | |
| SCHEMBL547985 | 0.80 | HTR1A (0.67) | HTR1ADRD2LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516227-B1 | Dry analytical element for lithium assay | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5245021-A | Lithium carbonate analysis | EASTMAN KODAK COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5188802-A | Containing dye derivative of 14-crown-4 ether; colorimetric analysis | EASTMAN KODAK COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0516227-A2 | Dry analytical element for lithium assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516226-A1 | Novel 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |
| US-5132436-A | Intermediates for making 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-07-21 | — | — | US | disclosed |