Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045186 | 0.86 | HDAC8 (0.47) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL3045183 | 0.86 | HDAC8 (0.47) | NPSR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL17082502 | 0.81 | RAB9A (0.46) | TDP1NPSR1PDK1PDK2PDK3 | |
| SCHEMBL8176078 | 0.78 | SLC7A5 (0.51) | NPSR1ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL3054398 | 0.77 | RAB9A (0.61) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12401982 | 0.77 | MEN1 (0.49) | TDP1NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7936084 | 0.76 | HCRTR2 (0.45) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL3047727 | 0.76 | HCRTR2 (0.45) | TDP1PDK1PDK2PDK3PDK4 | |
| SCHEMBL13224065 | 0.76 | MMP2 (0.50) | NPSR1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3042876 | 0.76 | MMP2 (0.50) | NPSR1ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086963-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | disclosed |
| WO-2008060927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-22 | — | — | WO | disclosed |