SCHEMBL8193085

SCHEMBL8193085

CON=C(C(=O)OC)c1c(C)cccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.40
HIF1A Q16665 8/20 0.38
TLR2 O60603 1/20 0.36
ERN1 O75460 1/20 0.36
TLR1 Q15399 1/20 0.36
TLR6 Q9Y2C9 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CYP19A1 P11511 2/20 0.36
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8193082 1.00 ALDH1A1 (0.40) ALDH1A1TSHRHIF1ATLR2ERN1
SCHEMBL7594989 0.86 HIF1A (0.43) ALDH1A1HIF1ACA1CA2POLB
SCHEMBL7645228 0.86 HIF1A (0.43) ALDH1A1HIF1ACA1CA2POLB
SCHEMBL6355686 0.79 POLB (0.46) HIF1APOLBRAB9A
SCHEMBL7209021 0.78 HIF1A (0.48) ALDH1A1TSHRHIF1ATLR2ERN1
SCHEMBL8835428 0.78 HIF1A (0.48) ALDH1A1TSHRHIF1ATLR2ERN1
SCHEMBL7206001 0.78 HIF1A (0.48) ALDH1A1TSHRHIF1ATLR2ERN1
SCHEMBL5713091 0.76 HIF1A (0.44) HIF1APOLBRAB9A
SCHEMBL5713110 0.76 HIF1A (0.44) ALDH1A1HIF1A
SCHEMBL5713111 0.76 HIF1A (0.44) ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000053585-A1 AMIDE AND ESTER FUNGICIDES AND ARTHROPODICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-09-14 WO disclosed