Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645228 | 0.89 | HIF1A (0.43) | POLBHIF1AKMT2A | |
| SCHEMBL7594989 | 0.89 | HIF1A (0.43) | POLBHIF1AKMT2A | |
| SCHEMBL6363655 | 0.86 | POLB (0.40) | POLBCES2CES1RAB9AKRAS | |
| SCHEMBL6363913 | 0.85 | CA12 (0.47) | POLBHIF1ACES2CES1RAB9A | |
| SCHEMBL8193085 | 0.79 | ALDH1A1 (0.40) | POLBHIF1ARAB9A | |
| SCHEMBL8193082 | 0.79 | ALDH1A1 (0.40) | POLBHIF1ARAB9A | |
| SCHEMBL6357822 | 0.79 | CES2 (0.50) | POLBCES2CES1RAB9AKRAS | |
| SCHEMBL5713110 | 0.78 | HIF1A (0.44) | HIF1AKMT2A | |
| SCHEMBL5713091 | 0.78 | HIF1A (0.44) | POLBHIF1ARAB9AKMT2A | |
| SCHEMBL5713111 | 0.78 | HIF1A (0.44) | HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124498-A1 | Halobenzyl substituted phenylaceto esters and amides and use thereof for prevention of harmful organisms | BAYER CROPSCIENCE AG (DE) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124498-A1 | Halobenzyl substituted phenylaceto esters and amides and use thereof for prevention of harmful organisms | HDHD5, GNPAT, PGLS | POLB 265/4885HIF1A 2259/4885CES2 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.