SCHEMBL819310

SCHEMBL819310

C[C@@H](O)c1cccc(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ACP3 P15309 1/20 0.47
UGT2B7 P16662 1/20 0.47
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
SLC2A1 P11166 2/20 0.45
TSHR P16473 2/20 0.44
RECQL P46063 1/20 0.44
PNMT P11086 1/20 0.44
NR4A2 P43354 1/20 0.42
AOC3 Q16853 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343771 1.00 MEN1 (0.47) MEN1KMT2AACP3UGT2B7ADRB2
SCHEMBL819047 1.00 MEN1 (0.47) MEN1KMT2AACP3UGT2B7ADRB2
SCHEMBL15943135 1.00 MEN1 (0.47) MEN1KMT2AACP3UGT2B7ADRB2
SCHEMBL27382952 0.98 MEN1 (0.46) MEN1KMT2AACP3UGT2B7ADRB2
Hydrochloric Acid SCHEMBL7753577 0.98 SLC2A1 (0.48) MEN1KMT2AACP3UGT2B7ADRB2
Hydrochloric Acid SCHEMBL27389833 0.98 SLC2A1 (0.48) MEN1KMT2AACP3UGT2B7ADRB2
Oxalic Acid SCHEMBL27380050 0.90 MEN1 (0.49) MEN1KMT2AACP3ADRB2ADRB1
Fumaric Acid SCHEMBL27299351 0.86 ALDH1A1 (0.50) MEN1KMT2AACP3ADRB2ADRB1
SCHEMBL28951519 0.84 ACP3 (0.46) ACP3ADRB2ADRB1ADRB3SLC2A1
SCHEMBL9331659 0.83 UGT2B7 (0.56) MEN1KMT2AUGT2B7ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776301-A Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-04-08 CN claimed
CN-104402661-A Economic and efficient method for asymmetric synthesis of R-configuration aromatic alcohol through copper salt catalysis UNIV JIANGNAN 2015-03-11 CN claimed
CN-104311393-A Preparation method of R-1-(3-chlorphenyl) ethanol and ester thereof WANG TONGJUN 2015-01-28 CN claimed
US-20250188068-A1 AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-06-12 US disclosed
EP-4561561-A2 SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR Septerna, Inc. (US) 2025-06-04 EP disclosed
CN-119776301-A Alcohol dehydrogenase, recombinant genetically engineered bacterium and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-04-08 CN disclosed
EP-4490150-A1 AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2025-01-15 EP disclosed
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN SHIRE HUMAN GENETIC THERAPIES (US) 2024-06-20 US disclosed
US-11999717-B2 Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2024-06-04 US disclosed
US-20240174683-A1 MAP4K1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-05-30 US disclosed
CN-114728168-B Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use 吉利德科学公司 2024-04-09 CN disclosed
US-20110112118-A1 2,4-Diaminoquinazolines for Spinal Muscular Atrophy FAMILIES OF SPINAL MUSCULAR ATROPHY (US) 2011-05-12 US disclosed
US-7888366-B2 2,4-diaminoquinazolines for spinal muscular atrophy FAMILIES OF SPINAL MUSCULAR ATROPHY (US) 2011-02-15 US disclosed
EP-1765810-A1 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY Decode Chemistry, Inc. (US) 2007-03-28 EP disclosed
CN-1894213-A Substituted tetrahydrocarbazole and cyclopentanoindole derivatives MERCK & CO INC (CA) 2007-01-10 CN disclosed
US-7019022-B2 Substituted tetrahydrocarbazole and cyclopentanoindole derivatives MERCK FROSST CANADA & CO. (CA) 2006-03-28 US disclosed
WO-2005123724-A1 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY DECODE CHEMISTRY, INC. (US) 2005-12-29 WO disclosed
US-20050288314-A1 2,4-diaminoquinazolines for spinal muscular atrophy DECODE CHEMISTRY, INC. (US) 2005-12-29 US disclosed
US-20050154044-A1 Substituted tetrahydrocarbazole and cyclopentanoindole derivatives MERCK FROSST CANADA LTD. (CA) 2005-07-14 US disclosed
CN-1034497-C Process for the preparation of aromatic aminoalcohol derivatives useful for the treatment of diabetes and obesity SANKYO CO (JP) 1997-04-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110112118-A1 2,4-Diaminoquinazolines for Spinal Muscular Atrophy SMN1; SMN2, MUSK, MYO3B MEN1 2282/4885KMT2A 91/4885ACP3 3962/4885
US-20050288314-A1 2,4-diaminoquinazolines for spinal muscular atrophy SMN1; SMN2, MUSK, MYO3B MEN1 2282/4885KMT2A 91/4885ACP3 3962/4885
US-20240174683-A1 MAP4K1 INHIBITORS MAP3K4, MAP4K4, MAP4K1 MEN1 468/4885KMT2A 2250/4885ACP3 259/4885
US-11999717-B2 Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof LPAR3, LPAR1, LPAR2 MEN1 4586/4885KMT2A 1878/4885ACP3 250/4885
US-20250188068-A1 AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS LPAR1, LPAR2, LPAR3 MEN1 3284/4885KMT2A 3794/4885ACP3 1203/4885
US-20050154044-A1 Substituted tetrahydrocarbazole and cyclopentanoindole derivatives PTGIR, PTGDR, PTGDR2 MEN1 4580/4885KMT2A 4598/4885ACP3 3654/4885
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK1, KLK4 MEN1 1066/4885KMT2A 659/4885ACP3 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.