Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 3/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 7/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TERF2 | Q15554 | 7/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13336390 | 0.84 | — | — | |
| SCHEMBL13363193 | 0.84 | — | — | |
| SCHEMBL8290665 | 0.75 | GAA (0.42) | PPIAPSMB9PSMB8GAATERF2 | |
| SCHEMBL12856031 | 0.75 | GAA (0.42) | PPIAPSMB9PSMB8GAATERF2 | |
| SCHEMBL8192216 | 0.74 | FAP (0.41) | — | |
| SCHEMBL12856032 | 0.69 | PPIA (0.38) | PPIAPSMB9PSMB8GAATERF2 | |
| SCHEMBL13336393 | 0.69 | FAP (0.36) | — | |
| SCHEMBL13363332 | 0.69 | FAP (0.36) | — | |
| SCHEMBL8201674 | 0.69 | FAP (0.36) | — | |
| SCHEMBL8289629 | 0.67 | GAA (0.38) | GAACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070733-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |