Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | BPTF | Q12830 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827845 | 1.00 | ALOX15 (0.41) | ALOX15LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL12874856 | 1.00 | ALOX15 (0.41) | ALOX15LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL12361763 | 1.00 | ALOX15 (0.41) | ALOX15LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL819558 | 0.96 | LMNA (0.38) | ALOX15LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL819464 | 0.89 | — | — | |
| SCHEMBL1620209 | 0.80 | ALDH1A1 (0.36) | ALOX15LMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL23291839 | 0.76 | — | — | |
| SCHEMBL19305057 | 0.76 | — | — | |
| SCHEMBL3665210 | 0.76 | — | — | |
| SCHEMBL1621735 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | claimed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | claimed |
| US-10081688-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2018-09-25 | — | — | US | disclosed |
| US-20170002112-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-9447213-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20140275403-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20110288200-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2382241-A2 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085631-A2 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |