Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465020 | 1.00 | CTSK (0.33) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL8193600 | 1.00 | CTSK (0.33) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL24670538 | 0.86 | CA12 (0.31) | CA1CA7CA12CA14NFKB1 | |
| SCHEMBL7038864 | 0.85 | CA12 (0.30) | CA1CA7CA12CA14PTGES | |
| SCHEMBL16808277 | 0.85 | CA12 (0.30) | CA1CA7CA12CA14PTGES | |
| SCHEMBL19460142 | 0.83 | CA12 (0.35) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL24669520 | 0.83 | CA1 (0.36) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL3216144 | 0.83 | DGAT1 (0.32) | CA1CA7CA12CA14NFKB1 | |
| SCHEMBL22730755 | 0.81 | CA12 (0.43) | CTSKCA1CA7CA12CA14 | |
| SCHEMBL18121932 | 0.81 | CA12 (0.31) | CTSKCA1CA7CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100260-A | ((3-(1-(2-FLUORO-BIPHENYL-4-YL)-ETHYL)-ISOXAZOL-5-YLIMINO) -MORPHOLIN-4-YL-M ETHYL)-AMINE, FOR EXAMPLE; ADMINISTERING TO TREAT AUTOIMMUNE DISEASES AND INFLAMMATION | SUMITOMO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-08 | — | — | US | disclosed |