Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808277 | 1.00 | CA12 (0.30) | CA12CA1CA7CA14PTGES | |
| SCHEMBL8193600 | 0.85 | CTSK (0.33) | CA12CA1CA7CA14PTGES | |
| SCHEMBL8193597 | 0.85 | CTSK (0.33) | CA12CA1CA7CA14PTGES | |
| SCHEMBL19465020 | 0.85 | CTSK (0.33) | CA12CA1CA7CA14PTGES | |
| SCHEMBL24671528 | 0.83 | — | — | |
| SCHEMBL24670538 | 0.82 | CA12 (0.31) | CA12CA1CA7CA14PTGES | |
| SCHEMBL16808293 | 0.80 | — | — | |
| SCHEMBL19236012 | 0.80 | CA12 (0.34) | CA12CA1CA7CA14PTGES | |
| SCHEMBL24669520 | 0.79 | CA1 (0.36) | CA12CA1CA7CA14PTGES | |
| SCHEMBL19460142 | 0.79 | CA12 (0.35) | CA12CA1CA7CA14PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055214-A1 | Guanidinylation reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-20 | — | — | US | claimed |
| EP-0983232-B1 | GUANIDINYLATION REAGENTS | UNIV CALIFORNIA (US) | 2002-11-13 | — | — | EP | claimed |
| US-6072075-A | Guanidinylation reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-06 | — | — | US | claimed |
| US-20030055214-A1 | Guanidinylation reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-20 | — | — | US | disclosed |
| EP-0983232-B1 | GUANIDINYLATION REAGENTS | UNIV CALIFORNIA (US) | 2002-11-13 | — | — | EP | disclosed |
| US-6380358-B1 | USING IN SOLID PHASE SYNTHESIS; FOR EXAMPLE, N-N'-DI-BOC-N?-TRIFLUOROMETHMESULFONYL-GUANIDINE TO YIELD N-PROTECTED GUANIDINE DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-30 | — | — | US | disclosed |
| US-6072075-A | Guanidinylation reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0983232-A2 | GUANIDINYLATION REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998052917-A2 | GUANIDINYLATION REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055214-A1 | Guanidinylation reagents | GDA, GMPS, GNMT | CA12 4765/4885CA1 4741/4885CA7 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.