Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598350 | 0.86 | HCRTR1 (0.39) | RIPK1ABHD6DAGLAMEN1ALDH1A1 | |
| SCHEMBL598349 | 0.86 | HCRTR1 (0.39) | RIPK1ABHD6DAGLAMEN1ALDH1A1 | |
| SCHEMBL1231214 | 0.80 | RIPK1 (0.38) | RIPK1ABHD6DAGLAKMT2ATSHR | |
| SCHEMBL1231216 | 0.80 | RIPK1 (0.38) | RIPK1ABHD6DAGLAKMT2ATSHR | |
| SCHEMBL597215 | 0.76 | SMN1; SMN2 (0.38) | RIPK1MEN1KMT2ATSHRMME | |
| SCHEMBL9974772 | 0.76 | CYP3A4 (0.36) | RIPK1ALDH1A1KMT2ATSHRMME | |
| SCHEMBL18175828 | 0.76 | CYP3A4 (0.36) | RIPK1ALDH1A1KMT2ATSHRMME | |
| SCHEMBL8181740 | 0.76 | HCRTR1 (0.38) | ABHD6DAGLAMEN1ALDH1A1KMT2A | |
| SCHEMBL599395 | 0.76 | SMN1; SMN2 (0.38) | RIPK1MEN1KMT2ATSHRMME | |
| SCHEMBL9929765 | 0.76 | CYP3A4 (0.36) | RIPK1ALDH1A1KMT2ATSHRMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083967-A2 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2008-07-17 | — | — | WO | disclosed |