Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370074 | 0.66 | HSD17B10 (0.59) | MEN1ALDH1A1KMT2AUSP2HPGD | |
| SCHEMBL4124403 | 0.65 | NCEH1 (0.55) | MEN1ALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL4960213 | 0.64 | NCEH1 (0.42) | MEN1ALDH1A1KMT2AUSP2HPGD | |
| SCHEMBL27990064 | 0.63 | TAS1R3 (0.45) | MEN1KMT2ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL7964391 | 0.63 | SMN1; SMN2 (0.51) | MEN1ALDH1A1KMT2AUSP2HPGD | |
| SCHEMBL13301683 | 0.61 | KMT2A (0.41) | MEN1ALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL22129863 | 0.60 | HPRT1 (0.50) | MEN1ALDH1A1KMT2AUSP2HPGD | |
| SCHEMBL4959304 | 0.59 | PTPN22 (0.60) | ALDH1A1USP2HPGDHSD17B10LDHA | |
| Hydrochloric Acid SCHEMBL11726958 | 0.56 | KMT2A (0.57) | MEN1ALDH1A1KMT2AUSP2HPGD | |
| SCHEMBL10333567 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000064-A1 | COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999001455-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-14 | — | — | WO | disclosed |