Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192345 | 0.84 | LMNA (0.41) | MEN1PKMKMT2ALMNASTAT3 | |
| SCHEMBL5556419 | 0.82 | LMNA (0.43) | MEN1KMT2ALMNAALDH1A1AR | |
| SCHEMBL8191430 | 0.81 | ALDH1A1 (0.39) | MEN1PKMKMT2ALMNAALDH1A1 | |
| SCHEMBL8191133 | 0.80 | LMNA (0.53) | MEN1PKMKMT2ALMNAALDH1A1 | |
| SCHEMBL20535567 | 0.79 | LMNA (0.44) | MEN1PKMKMT2ALMNAALDH1A1 | |
| SCHEMBL8190016 | 0.79 | MAPT (0.41) | MEN1PKMKMT2ALMNASTAT3 | |
| SCHEMBL21501953 | 0.78 | LMNA (0.52) | MEN1PKMKMT2ALMNASTAT3 | |
| SCHEMBL25139738 | 0.77 | ALDH1A1 (0.53) | MEN1PKMKMT2ALMNAALDH1A1 | |
| SCHEMBL4892197 | 0.76 | MEN1 (0.47) | MEN1PKMKMT2ALMNASTAT3 | |
| SCHEMBL26830787 | 0.76 | MAPT (0.56) | MEN1KMT2ALMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096743-A | 1,2,3,4-tetrahydroquinoxalinedione derivative | YAMANOUCHI PHARMACEUTICALS CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0784054-A1 | 1,2,3,4-TETRAHYDROQUINOXALINEDIONE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-16 | — | — | EP | disclosed |