SCHEMBL8195059

SCHEMBL8195059

Cc1ccc(O[Ti](Cc2ccccc2)(Oc2ccc(C)cc2)Oc2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 3/20 0.40
CYP2C19 P33261 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
DRD2 P14416 2/20 0.39
DRD4 P21917 2/20 0.39
DRD3 P35462 2/20 0.39
LTA4H P09960 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
ACHE P22303 2/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
CYP19A1 P11511 1/20 0.37
AR P10275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7172909 0.86 TSHR (0.40) LMNAKMT2ACYP2C19GAADRD4
SCHEMBL8183505 0.85 LMNA (0.42) LMNAMEN1KMT2AMAPTHTT
SCHEMBL8195062 0.73 SCN4A (0.44) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL6912966 0.70 TSHR (0.42) MAPTLTA4HTSHRALDH1A1
SCHEMBL128703 0.69 LMNA (0.67) LMNAMAPTCYP2C19GAAAR
SCHEMBL9274672 0.69 MAPT (0.54) LMNAMEN1KMT2AMAPTHTT
SCHEMBL7590714 0.69 TSHR (0.39) LMNAKMT2ACYP2C19DRD4LTA4H
SCHEMBL7593017 0.69 TSHR (0.39) LMNAKMT2ACYP2C19GAADRD4
P-Xylene SCHEMBL11045590 0.68 LMNA (0.54) LMNAHTTCYP2C19POLBACHE
SCHEMBL7593470 0.68 ACHE (0.48) LMNAMEN1KMT2AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6111040-A Process for the production of olefinic polymers NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-08-29 US disclosed
EP-0745616-B1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO LTD (JP) 1999-04-07 EP disclosed
US-5750454-A Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0748823-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-18 EP disclosed
EP-0745616-A1 Catalyst composition and process for the production of olefinic polymers NIPPON OIL CO. LTD. (JP) 1996-12-04 EP disclosed