SCHEMBL128703

SCHEMBL128703

Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
CYP1A2 P05177 1/20 0.67
PTGS1 P23219 1/20 0.67
SLC6A2 P23975 1/20 0.67
CYP2C19 P33261 1/20 0.67
PTGS2 P35354 1/20 0.67
SLC6A3 Q01959 1/20 0.67
HIF1A Q16665 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
MAOB P27338 5/20 0.64
GAA P10253 1/20 0.64
MAPT P10636 1/20 0.64
MAOA P21397 1/20 0.64
RAB9A P51151 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
AR P10275 1/20 0.62
BCHE P06276 1/20 0.60
NR4A1 P22736 1/20 0.58
NR4A2 P43354 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128671 0.94 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8736979 0.94 LMNA (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11611966 0.92 LMNA (0.58) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL2339524 0.91 MAOB (0.65) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL14176678 0.89 MEN1 (0.55) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8737849 0.89 AR (0.65) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8929713 0.89 MAOB (0.69) MAOBMAPTMAOARAB9ASMN1; SMN2
SCHEMBL891195 0.89 MAOB (0.69) MAOBMAPTMAOARAB9ASMN1; SMN2
SCHEMBL762195 0.89 MAOB (0.69) MAOBMAPTMAOARAB9ASMN1; SMN2
SCHEMBL8930213 0.89 MAOB (0.69) MAOBMAPTMAOARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107356682-B HPLC method for detecting 4-benzyloxy benzylidene aniline in 4-benzyloxy benzylidene-4-fluoroaniline 先声药业有限公司 2021-06-29 CN claimed
CN-112209900-A Method for preparing 4-cyclohexylmorpholine compound by using lignin model compound 华东师范大学 2021-01-12 CN claimed
CN-107356682-A A kind of HPLC methods of 4- benzyloxy benzylidene anilines in detection 4- benzyloxy benzylidene -4- fluoroanilines 南京先声东元制药有限公司 2017-11-17 CN claimed
CN-102325659-B Novel color-forming compounds and use thereof in imaging members and methods ZINK IMAGING INC 2015-04-01 CN claimed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US claimed
CN-101495120-A Composition for induction or inhibition of stem cell differentiation CHOONGWAE PHARMA CORP (KR) 2009-07-29 CN claimed
EP-2029142-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION Choongwae Pharma Corporation (KR) 2009-03-04 EP claimed
WO-2007139346-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2007-12-06 WO claimed
US-6806384-B2 VIA TREATING N-CARBAMATE-PROTECTED BETA-AMINOEPOXIDE WITH ACID FORMING 5-HYDROXYMETHYL-2-OXAZOLIDINONE, THEN OXIDIZING IN 2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY AND HYPOCHLORITE FORMING 4-BENZYL-2-OXO-5-OXAZOLIDINECARBOXYLIC ACID; CRYSTALLIZATION AJINOMOTO CO., INC. (JP) 2004-10-19 US claimed
US-6630512-B2 Antiinflammatory agents; autoimmune disease BIOGEN, INC. 2003-10-07 US claimed
EP-0805796-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1997-11-12 EP claimed
EP-0796239-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE (S,S) AMINOEPOXIDES, KEY INTERMEDIATES FOR HIV PROTEASE INHIBITORS, VIA THEIR CHLOROHYDRINES BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1997-09-24 EP claimed
US-5550291-A Process for key intermediates for HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH, INC. (CA) 1996-08-27 US claimed
WO-1996022966-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1996-08-01 WO claimed
WO-1996017821-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE (S,S) AMINOEPOXIDES, KEY INTERMEDIATES FOR HIV PROTEASE INHIBITORS, VIA THEIR CHLOROHYDRINES BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE (CA) 1996-06-13 WO claimed
EP-0604368-A1 Anti retroviral hydrazine derivatives CIBA-GEIGY AG (CH) 1994-06-29 EP claimed
EP-0126974-B1 CARBOXYALKYL PEPTIDE DERIVATIVES G.D. Searle & Co. (US) 1988-06-15 EP claimed
EP-0126974-A1 Carboxyalkyl peptide derivatives G.D. Searle & Co. (US) 1984-12-05 EP claimed
US-4029690-A WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed
US-4029683-A WITH A SCHIFF BASE, CHRYSANTHEMATE SYNTHESIS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 LMNA 194/4885CYP1A2 3259/4885PTGS1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.