Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149478 | 1.00 | LMNA (0.35) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8191192 | 0.97 | — | — | |
| SCHEMBL8188042 | 0.88 | — | — | |
| SCHEMBL10063278 | 0.88 | — | — | |
| SCHEMBL926290 | 0.80 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL455669 | 0.80 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL920169 | 0.80 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9700524 | 0.80 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL19812440 | 0.77 | SMN1; SMN2 (0.33) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL24175245 | 0.76 | THRB (0.44) | LMNAMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074450-A2 | NON-PEPTIDIC RENIN INHIBITORS NITRODERIVATIVES | NICOX S.A. (FR) | 2008-06-26 | — | — | WO | disclosed |