Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866097 | 0.84 | EPHX1 (0.52) | EPHX1ACHEALDH1A1RAB9AMAPT | |
| SCHEMBL590532 | 0.83 | EPHX1 (0.59) | EPHX1ACHEALDH1A1RAB9AMAPT | |
| SCHEMBL7447192 | 0.82 | EPHX1 (0.53) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL1126445 | 0.81 | ACHE (0.52) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL11640899 | 0.79 | GAA (0.42) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL9197261 | 0.79 | EPHX1 (0.55) | EPHX1ACHEALDH1A1RAB9AMAPT | |
| SCHEMBL7455335 | 0.78 | EPHX1 (0.46) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL11627977 | 0.78 | ALDH1A1 (0.58) | EPHX1ACHEALDH1A1RAB9AHPGD | |
| SCHEMBL9395279 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL28436498 | 0.78 | EPHX1 (0.53) | EPHX1ACHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040289-A | ACTIVE DRUG TREATING OBESITY | DR. KARL THOMAE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |