SCHEMBL819653

SCHEMBL819653

C1CCCC([N]C2CCCCCCC2)CCC1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
HIF1A Q16665 1/20 0.50
ALDH1A1 P00352 4/20 0.45
SIGMAR1 Q99720 3/20 0.35
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49195 1.00 EPHX1 (0.50) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL49353 1.00 EPHX1 (0.50) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL7647781 1.00 EPHX1 (0.50) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL7644168 1.00 EPHX1 (0.50) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL2917831 1.00 EPHX1 (0.50) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL1679057 0.96 EPHX1 (0.47) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL1678725 0.96 EPHX1 (0.47) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL1679055 0.96 EPHX1 (0.47) EPHX1HIF1AALDH1A1SIGMAR1HSD17B10
SCHEMBL49819 0.96 EPHX1 (0.44) EPHX1HIF1AALDH1A1SIGMAR1KMT2A
SCHEMBL1678970 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
US-20200247957-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-08-06 US disclosed
EP-3689891-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION Kyushu University, National University Corporation (JP) 2020-08-05 EP disclosed
EP-3118205-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
EP-3269724-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-07-30 US disclosed
US-10130634-B2 Therapeutic agent for ophthalmic disease MITSUBISHI TANABE PHARMA CORPORATION (JP) 2018-11-20 US disclosed
EP-2963047-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2018-11-14 EP disclosed
EP-2963046-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2018-10-17 EP disclosed
US-20180243732-A1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-08-30 US disclosed
WO-2007023618-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-01 WO disclosed
EP-0885237-B1 OLIGONUCLEOTIDE ANALOGUES ISIS PHARMACEUTICALS INC (US) 2003-09-10 EP disclosed
US-6562960-B1 Oligonucleotide analogues ISIS PHARMACEUTICALS, INC. 2003-05-13 US disclosed
US-6455458-B1 HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-24 US disclosed
EP-0885237-A1 OLIGONUCLEOTIDE ANALOGUES Novartis AG (CH) 1998-12-23 EP disclosed
US-5677299-A VASOPRESSIN OR OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1997-10-14 US disclosed
WO-1997032887-A1 OLIGONUCLEOTIDE ANALOGUES NOVARTIS AG (CH) 1997-09-12 WO disclosed
US-5498609-A Benzoazepinyl compounds as oxytocin and vasopressin antagonists OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0612319-A1 BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-08-31 EP disclosed
WO-1994004525-A1 BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1994-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180243732-A1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME TFRC, IDO1, H1-0 EPHX1 3739/4885HIF1A 616/4885ALDH1A1 2768/4885
US-20200247957-A1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION OR51E2, WEE2, SLC39A11 EPHX1 3584/4885HIF1A 720/4885ALDH1A1 1421/4885
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same TFRC, IDO1, H1-0 EPHX1 3739/4885HIF1A 616/4885ALDH1A1 2768/4885
US-10130634-B2 Therapeutic agent for ophthalmic disease MITF, UACA, VEGFA EPHX1 1625/4885HIF1A 100/4885ALDH1A1 289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.