Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 10/20 | 0.42 |
| ▸ | GUCY1B2 | O75343 | 5/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 5/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 5/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035132 | 0.93 | FOLH1 (0.36) | TACR3GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL13035288 | 0.93 | FOLH1 (0.36) | TACR3GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL8199491 | 0.90 | PTGER4 (0.37) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CNR1 | |
| SCHEMBL8194184 | 0.90 | PTGER4 (0.37) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CNR1 | |
| SCHEMBL8191808 | 0.88 | TACR3 (0.39) | TACR3GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL13035050 | 0.86 | MT-CO2 (0.35) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CNR1 | |
| SCHEMBL8194380 | 0.84 | GUCY1B2 (0.38) | TACR3GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL13035249 | 0.83 | PTGER4 (0.38) | TACR3GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL13035264 | 0.82 | PTGER4 (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CNR1 | |
| SCHEMBL13035109 | 0.82 | PTGER4 (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | SCHERING CORPORATION | 2010-11-25 | — | — | US | disclosed |
| US-20100298314-A1 | NOVEL JNK INHIBITORS | SCHERING CORPORATION | 2010-11-25 | — | — | US | disclosed |
| WO-2008082490-A2 | NOVEL JNK INHIBITORS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | MAPK1, MAPKAPK2, MAP4K2 | TACR3 4233/4885GUCY1B2 2678/4885GUCY1A2 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.