Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196356 | 0.75 | HSD17B10 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL8121645 | 0.74 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1506403 | 0.72 | STS (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7485862 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6333334 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23090404 | 0.69 | ALDH1A1 (0.57) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7485060 | 0.68 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6333760 | 0.67 | ALDH1A1 (0.59) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7536889 | 0.67 | NISCH (0.36) | KDM4E | |
| SCHEMBL647390 | 0.67 | NPC1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |